Customer Profile: Dr. Pascale Jackers
Dr. Pascale Jackers is a senior scientist at the University of Liege in Belgium. She studies systems biology in the well-established Mass Spectrometry Laboratory under Professor Edwin De Pauw. Her latest project with Ludesi involved the analysis of a large-scale time-course experiment.
Read below for Dr. Jackers's answers to our seven customer profile questions:
How would you describe the overall goal of your research?
My foremost goal is to understand systems biology using data from proteomics (including PTMs) and transcriptomics when available.
What is your goal specifically for your 2D gel based research?
To obtain accurate data with correctly identified proteins. Such data could be used as a basic support to study PTMs and systems biology.
What type of samples are you primarily working with?
Mouse brain tissue
What have you achieved by using 2D gels?
We are still in the process of completing this project, so you could say our goals have not been completely achieved yet.
What type of Ludesi analysis do you primarily use (REDFIN Solo, Basic, or Pro)?
Ludesi Pro analysis
What made you choose Ludesi's analysis service?
The main reason is the all-to-all matching algorithm employed in the Ludesi Analysis Center, where reference-free matching is performed. Statistically, that kind of algorithm leads to a better accuracy compared to other software that require the researcher to select a reference gel. Another reason is the Combined Correctness algorithm that is used by an independent team of experts to quality control the analysis of the gels.
How does using the analysis service help you in your work?
I've got higher confidence in the generated results.
Read more about Dr. Jackers's work in some of her recent publications:
VALAPODYN: Validated Predictive Dynamic Model of Complex Intracellular
Pathways Related to Cell Death and Survival
A. Depaulis, E. Vafiadaki, P. Jackers, D. A. Arvanitis, O. Kel-Margoulis,
E. Wingender, T. Vujasinovic, D. Greenberg, H. Soreq, E. De Pauw, J. B.
Dumas Milne Edwards, D. Sanoudou.
European Journal of Human Genetics (2007) 15 (suppl. 1), 307
Developing predictive dynamic models of complex intracellular networks
for neurological disease
E. Vafiadaki, A. Depaulis, P. Jackers, D. Arvanitis, O. Kel-Margoulis, E.
Wingender, T. Vujasinovic, D. Greenberg, H. Soreq, E. DePauw, J. B.
Dumas,M. Edwards and D. Sanoudou.
FEBS Journal (2008) 275 (suppl. 1), 206.
